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John L. P. (Seamus) Thompson
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Director of Clinical Trials Activities, Biostatistics
Clinical Professor of Biostatistics, Mailman School of Public Health
and:
Clinical Professor of Neurology, College of Physicians and Surgeons
Co-Director, Integrative Health Sciences Core,
Columbia Center for Environmental Health in Northern Manhattan
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| Seamus (J. L. P.) Thompson, PhD, has extensive experience in implementing methodologically innovative clinical trials in close collaboration with clinical leaders using state-of-the-art data management systems. Dr. Thompson directs the Statistical Analysis Center for Clinical Trials (SAC) within the Department of Biostatistics, which offers each trial a dedicated center providing all needed statistical and data management resources and a comprehensive website and web-based trial management capabilities. This approach has allowed the SAC to efficiently apply advanced trial designs developed by Biostatistics faculty members in a series of NIH-funded trials including WARSS (the Warfarin versus Aspirin for Recurrent Stroke Study, which employed a double-blinding algorithm developed by Dr. Thompson); TNK-S2B, comparing two interventions for acute stroke; and QALS, for the neurodegenerative disorder ALS. The largest SAC trial, WARCEF (Warfarin Versus Aspirin for low Cardiac Ejection Fraction), has recruited over 1800 patients in nine countries. The SAC also provides comprehensive statistical and data management capabilities for many national and international projects in epidemiology, including Arsenic Exposure in Bangladesh; the World Trade Center Research Program; the Puerto Rican Asthma Study; Diabetes Mellitus and Periodontal Disease in Children; and HIV in South Africa. Many of these projects originate in the Columbia Center for Environmental Health in Northern Manhattan, where Dr. Thompson is currently Co-Director of the Integrative Health Sciences Core.
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